Internalization of blocking antibodies against mannose-6-phosphate specific receptors.

Antibodies against mannose-6-phosphate specific receptors inhibit the receptor-dependent endocytosis of exogenous lysosomal enzymes as well as the sorting of endogenous lysosomal enzymes. This inhibition was correlated with an apparent loss of the receptors. We report here that treatment of cells wi...

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Bibliographic Details
Published in:EMBO J
Main Authors: Gartung, C, Braulke, T, Hasilik, A, von Figura, K
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1985
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554409/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3161725/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1985.tb03842.x
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