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Internalization of blocking antibodies against mannose-6-phosphate specific receptors.

Antibodies against mannose-6-phosphate specific receptors inhibit the receptor-dependent endocytosis of exogenous lysosomal enzymes as well as the sorting of endogenous lysosomal enzymes. This inhibition was correlated with an apparent loss of the receptors. We report here that treatment of cells wi...

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Autors principals: Gartung, C, Braulke, T, Hasilik, A, von Figura, K
Format: Artigo
Idioma:Inglês
Publicat: 1985
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC554409/
https://ncbi.nlm.nih.gov/pubmed/3161725
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