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Antibody to mannose 6-phosphate specific receptor induces receptor deficiency in human fibroblasts.

Polyclonal antibodies to the mannose 6-phosphate specific receptor from human liver inhibited the endocytosis of lysosomal enzymes in fibroblasts by greater than 95% and enhanced 3-20-fold the secretion of precursors of lysosomal enzymes in these cells. Exposing fibroblasts for 4 h to antibody resul...

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Bibliografische gegevens
Hoofdauteurs: von Figura, K, Gieselmann, V, Hasilik, A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1984
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC557509/
https://ncbi.nlm.nih.gov/pubmed/6086314
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