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1.12 Å resolution crystal structure of the catalytic domain of the plasmid-mediated colistin resistance determinant MCR-2

MCR-2 confers resistance to colistin, a ‘last-line’ antibiotic against extensively resistant Gram-negative pathogens. It is a plasmid-encoded phosphoethanol­amine transferase that is closely related to MCR-1. To understand the diversity in the MCR family, the 1.12 Å resolution crystal structure of t...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Coates, Katie, Walsh, Timothy R., Spencer, James, Hinchliffe, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544000/
https://ncbi.nlm.nih.gov/pubmed/28777086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X17009669
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