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Structure of the catalytic domain of the colistin resistance enzyme MCR-1
BACKGROUND: Due to the paucity of novel antibiotics, colistin has become a last resort antibiotic for treating multidrug resistant bacteria. Colistin acts by binding the lipid A component of lipopolysaccharides and subsequently disrupting the bacterial membrane. The recently identified plasmid-encod...
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| Publié dans: | BMC Biol |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5031297/ https://ncbi.nlm.nih.gov/pubmed/27655155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0303-0 |
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