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In Vitro Study of ISApl1-Mediated Mobilization of the Colistin Resistance Gene mcr-1

The plasmid-mediated mcr-1 gene encodes a phosphoethanolamine transferase that confers resistance to polymyxins. The mcr-1 gene is associated with insertion sequence ISApl1 (IS30 family). In vitro mobilization assays demonstrated the functionality of the composite transposon structure ISApl1-mcr-1-I...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Poirel, Laurent, Kieffer, Nicolas, Nordmann, Patrice
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487687/
https://ncbi.nlm.nih.gov/pubmed/28416554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00127-17
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