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A Model for Transposition of the Colistin Resistance Gene mcr-1 by ISApl1

Analysis of mcr-1-containing sequences identified a common ∼2,607-bp DNA segment that in many cases is flanked on one or both ends by ISApl1. We present evidence that mcr-1 is mobilized by an ISApl1 composite transposon which has, in some cases, subsequently lost one or both copies of ISApl1. We als...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Snesrud, Erik, He, Susu, Chandler, Michael, Dekker, John P., Hickman, Alison B., McGann, Patrick, Dyda, Fred
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075121/
https://ncbi.nlm.nih.gov/pubmed/27620479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01457-16
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