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Ectopic expression of Cdk8 induces eccentric hypertrophy and heart failure

Widespread changes in cardiac gene expression occur during heart failure, yet the mechanisms responsible for coordinating these changes remain poorly understood. The Mediator complex represents a nodal point for modulating transcription by bridging chromatin-bound transcription factors with RNA poly...

詳細記述

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書誌詳細
出版年:JCI Insight
主要な著者: Hall, Duane D., Ponce, Jessica M., Chen, Biyi, Spitler, Kathryn M., Alexia, Adrianne, Oudit, Gavin Y., Song, Long-Sheng, Grueter, Chad E.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543923/
https://ncbi.nlm.nih.gov/pubmed/28768905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92476
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