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Development and characterization of naive single-type tumor antigen-specific CD8(+) T lymphocytes from murine pluripotent stem cells

Optimal approaches to differentiate tumor antigen-specific cytotoxic T lymphocytes (CTLs) from pluripotent stem cells (PSCs) remain elusive. In the current study, we showed that combination of in vitro priming through Notch ligands and in vivo development facilitated the generation of tumor Ag-speci...

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Foilsithe in:Oncoimmunology
Main Authors: Lei, Fengyang, Haque, Mohammad, Sandhu, Praneet, Ravi, Swetha, Song, Jianyong, Ni, Bing, Zheng, Songguo, Fang, Deyu, Jia, Hongyan, Yang, Jin-Ming, Song, Jianxun
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2017
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543906/
https://ncbi.nlm.nih.gov/pubmed/28811978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1334027
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