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Directed Differentiation of Induced Pluripotent Stem Cells towards T Lymphocytes

Adoptive cell transfer (ACT) of antigen-specific CD8(+) cytotoxic T lymphocytes (CTLs) is a promising treatment for a variety of malignancies (1). CTLs can recognize malignant cells by interacting tumor antigens with the T cell receptors (TCR), and release cytotoxins as well as cytokines to kill mal...

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Detalhes bibliográficos
Main Authors: Lei, Fengyang, Haque, Rizwanul, Xiong, Xiaofang, Song, Jianxun
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389997/
https://ncbi.nlm.nih.gov/pubmed/22617911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3986
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