Development and characterization of naive single-type tumor antigen-specific CD8(+) T lymphocytes from murine pluripotent stem cells

Optimal approaches to differentiate tumor antigen-specific cytotoxic T lymphocytes (CTLs) from pluripotent stem cells (PSCs) remain elusive. In the current study, we showed that combination of in vitro priming through Notch ligands and in vivo development facilitated the generation of tumor Ag-speci...

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Dades bibliogràfiques
Publicat a:Oncoimmunology
Autors principals: Lei, Fengyang, Haque, Mohammad, Sandhu, Praneet, Ravi, Swetha, Song, Jianyong, Ni, Bing, Zheng, Songguo, Fang, Deyu, Jia, Hongyan, Yang, Jin-Ming, Song, Jianxun
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Brief Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543906/
https://ncbi.nlm.nih.gov/pubmed/28811978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1334027
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