Development and characterization of naive single-type tumor antigen-specific CD8(+) T lymphocytes from murine pluripotent stem cells

Optimal approaches to differentiate tumor antigen-specific cytotoxic T lymphocytes (CTLs) from pluripotent stem cells (PSCs) remain elusive. In the current study, we showed that combination of in vitro priming through Notch ligands and in vivo development facilitated the generation of tumor Ag-speci...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Lei, Fengyang, Haque, Mohammad, Sandhu, Praneet, Ravi, Swetha, Song, Jianyong, Ni, Bing, Zheng, Songguo, Fang, Deyu, Jia, Hongyan, Yang, Jin-Ming, Song, Jianxun
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Brief Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543906/
https://ncbi.nlm.nih.gov/pubmed/28811978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1334027
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