Development and characterization of naive single-type tumor antigen-specific CD8(+) T lymphocytes from murine pluripotent stem cells

Optimal approaches to differentiate tumor antigen-specific cytotoxic T lymphocytes (CTLs) from pluripotent stem cells (PSCs) remain elusive. In the current study, we showed that combination of in vitro priming through Notch ligands and in vivo development facilitated the generation of tumor Ag-speci...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Lei, Fengyang, Haque, Mohammad, Sandhu, Praneet, Ravi, Swetha, Song, Jianyong, Ni, Bing, Zheng, Songguo, Fang, Deyu, Jia, Hongyan, Yang, Jin-Ming, Song, Jianxun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Brief Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543906/
https://ncbi.nlm.nih.gov/pubmed/28811978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1334027
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