c-Myc-Induced Survivin Is Essential for Promoting the Notch-Dependent T Cell Differentiation from Hematopoietic Stem Cells

Notch is indispensable for T cell lineage commitment, and is needed for thymocyte differentiation at early phases. During early stages of T cell development, active Notch prevents other lineage potentials including B cell lineage and myeloid cell (e.g., dendritic cell) lineage. Nevertheless, the pre...

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Bibliographic Details
Published in:Genes (Basel)
Main Authors: Haque, Rizwanul, Song, Jianyong, Haque, Mohammad, Lei, Fengyang, Sandhu, Praneet, Ni, Bing, Zheng, Songguo, Fang, Deyu, Yang, Jin-Ming, Song, Jianxun
Format: Artigo
Language:Inglês
Published: MDPI 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368701/
https://ncbi.nlm.nih.gov/pubmed/28272325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes8030097
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