C-Myc regulation by costimulatory signals modulates the generation of CD8(+) memory T cells during viral infection

The signalling mechanisms of costimulation in the development of memory T cells remain to be clarified. Here, we show that the transcription factor c-Myc in CD8(+) T cells is controlled by costimulatory molecules, which modulates the development of memory CD8(+) T cells. C-Myc expression was dramati...

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Veröffentlicht in:Open Biol
Hauptverfasser: Haque, Mohammad, Song, Jianyong, Fino, Kristin, Wang, Youfei, Sandhu, Praneet, Song, Xinmeng, Norbury, Christopher, Ni, Bing, Fang, Deyu, Salek-Ardakani, Shahram, Song, Jianxun
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736826/
https://ncbi.nlm.nih.gov/pubmed/26791245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150208
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