C-Myc regulation by costimulatory signals modulates the generation of CD8(+) memory T cells during viral infection

The signalling mechanisms of costimulation in the development of memory T cells remain to be clarified. Here, we show that the transcription factor c-Myc in CD8(+) T cells is controlled by costimulatory molecules, which modulates the development of memory CD8(+) T cells. C-Myc expression was dramati...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Haque, Mohammad, Song, Jianyong, Fino, Kristin, Wang, Youfei, Sandhu, Praneet, Song, Xinmeng, Norbury, Christopher, Ni, Bing, Fang, Deyu, Salek-Ardakani, Shahram, Song, Jianxun
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736826/
https://ncbi.nlm.nih.gov/pubmed/26791245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150208
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