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Potent Prearranged Positive Allosteric Modulators of the Glucagon‐like Peptide‐1 Receptor
Drugs that allosterically modulate G protein‐coupled receptor (GPCR) activity display higher specificity and may improve disease treatment. However, the rational design of compounds that target the allosteric site is difficult, as conformations required for receptor activation are poorly understood....
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| Publié dans: | ChemistryOpen |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5542757/ https://ncbi.nlm.nih.gov/pubmed/28794944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201700062 |
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