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Diastereoselective Au-Catalyzed Allene Cycloisomerizations to Highly Substituted Cyclopentenes

Site- and regiocontrolled Au-catalyzed allene carbocyclizations furnish highly substituted cyclopentenes in >1:1 dr. Significant substitution on the substrate is tolerated, with potential to install five contiguous stereocenters after alkene functionalization. Major challenges include identifying...

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Foilsithe in:Org Lett
Main Authors: Reeves, Ryan D., Phelps, Alicia M., Raimbach, William A. T., Schomaker, Jennifer M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542682/
https://ncbi.nlm.nih.gov/pubmed/28598168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01350
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