Novel application of the published kinase inhibitor set to identify therapeutic targets and pathways in triple negative breast cancer subtypes

Triple negative breast cancers (TNBCs) have high recurrence and metastasis rates. Acquisition of a mesenchymal morphology and phenotype in addition to driving migration is a consequential process that promotes metastasis. Although some kinases are known to regulate a mesenchymal phenotype, the role...

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Veröffentlicht in:PLoS One
Hauptverfasser: Matossian, Margarite D., Elliott, Steven, Hoang, Van T., Burks, Hope E., Phamduy, Theresa B., Chrisey, Douglas B., Zuercher, William J., Drewry, David H., Wells, Carrow, Collins-Burow, Bridgette, Burow, Matthew E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542472/
https://ncbi.nlm.nih.gov/pubmed/28771473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177802
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