Constitutive activation of MEK5 promotes a mesenchymal and migratory cell phenotype in triple negative breast cancer

Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited targeted therapeutic options. A defining feature of TNBC is the propensity to metastasize and acquire resistance to cytotoxic agents. Mitogen activated protein kinase (MAPK) and extracellular regulated kinase...

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Udgivet i:Oncoscience
Main Authors: Matossian, Margarite D., Hoang, Van T., Burks, Hope E., La, Jacqueline, Elliott, Steven, Brock, Courtney, Rusch, Douglas B., Buechlein, Aaron, Nephew, Kenneth P., Bhatt, Akshita, Cavanaugh, Jane E., Flaherty, Patrick T., Collins-Burow, Bridgette M., Burow, Matthew E.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131078/
https://ncbi.nlm.nih.gov/pubmed/34026925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.535
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