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MEK5-ERK5 Signaling in Cancer: Implications for Targeted Therapy

Mitogen-activated protein kinases (MAPKs) regulate diverse cellular processes including proliferation, cell survival, differentiation, and apoptosis. While conventional MAPK constituents have well-defined roles in oncogenesis, the MAPK kinase 5-extracellular signal-regulated kinase 5 (MEK5-ERK5) pat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Lett
Hauptverfasser: Hoang, Van T., Yan, Thomas J., Cavanaugh, Jane E., Flaherty, Patrick T., Beckman, Barbara S., Burow, Matthew E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901897/
https://ncbi.nlm.nih.gov/pubmed/28153789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.01.034
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