Quantification of transplant-derived circulating cell-free DNA in absence of a donor genotype

Quantification of cell-free DNA (cfDNA) in circulating blood derived from a transplanted organ is a powerful approach to monitoring post-transplant injury. Genome transplant dynamics (GTD) quantifies donor-derived cfDNA (dd-cfDNA) by taking advantage of single-nucleotide polymorphisms (SNPs) distrib...

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Pubblicato in:PLoS Comput Biol
Autori principali: Sharon, Eilon, Shi, Hao, Kharbanda, Sandhya, Koh, Winston, Martin, Lance R., Khush, Kiran K., Valantine, Hannah, Pritchard, Jonathan K., De Vlaminck, Iwijn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542400/
https://ncbi.nlm.nih.gov/pubmed/28771616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005629
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