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Oncogenic MNK signalling regulates the metastasis suppressor NDRG1

The protein N-myc down-regulated gene 1 (NDRG1) represses tumour metastasis. It is phosphorylated at several sites by serum and glucocorticoid-regulated kinase 1 (SGK1). Here we show that NDRG1 is also regulated by the oncogenic MAP kinase-interacting kinase (MNK) pathway, a target for cancer therap...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Tian, Shuye, Wang, Xuemin, Proud, Christopher G.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542254/
https://ncbi.nlm.nih.gov/pubmed/28545025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17555
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