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Dihydroartemisinin induces autophagy-dependent death in human tongue squamous cell carcinoma cells through DNA double-strand break-mediated oxidative stress

Dihydroartemisinin is an effective antimalarial agent with multiple biological activities. In the present investigation, we elucidated its therapeutic potential and working mechanism on human tongue squamous cell carcinoma (TSCC). It was demonstrated that dihydroartemisinin could significantly inhib...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shi, Xinli, Wang, Li, Li, Xiaoming, Bai, Jing, Li, Jianchun, Li, Shenghao, Wang, Zeming, Zhou, Mingrui
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542242/
https://ncbi.nlm.nih.gov/pubmed/28526807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17520
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