Egr-1 and RNA POL II facilitate glioma cell GDNF transcription induced by histone hyperacetylation in promoter II

The specific mechanisms for epigenetic regulation of gene transcription remain to be elucidated. We previously demonstrated that hyperacetylation of histone H3K9 in promoter II of glioma cells promotes high transcription of the glial cell line-derived neurotrophic factor (GDNF) gene. This hyperacety...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Bao-Le, Guo, Ting-Wen, Gao, Le-Le, Ji, Guang-Quan, Gu, Xiao-He, Shao, Yu-Qi, Yao, Rui-Qin, Gao, Dian-Shuai
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542170/
https://ncbi.nlm.nih.gov/pubmed/28187447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15126
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