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Histone hyperacetylation modulates spinal type II metabotropic glutamate receptor alleviating stress-induced visceral hypersensitivity in female rats

Stress is often a trigger to exacerbate chronic pain including visceral hypersensitivity associated with irritable bowel syndrome, a female predominant functional bowel disorder. Epigenetic mechanisms that mediate stress responses are a potential target to interfere with visceral pain. The purpose o...

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Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Cao, Dong-Yuan, Bai, Guang, Ji, Yaping, Karpowicz, Jane, Traub, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956148/
https://ncbi.nlm.nih.gov/pubmed/27385724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916660722
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