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Estradiol modulates visceral hyperalgesia by increasing thoracolumbar spinal GluN2B subunit activity in female rats

BACKGROUND: We previously reported estrogen modulates spinal NMDA receptor processing of colorectal pain through changes in spinal GluN1 subunit phosphorylation/expression. The purpose of the present study was to investigate whether spinal GluN2B containing NMDA receptors are involved in estrogen mo...

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Publicado en:Neurogastroenterol Motil
Main Authors: Ji, Yaping, Bai, Guang, Cao, Dong-Yuan, Traub, Richard J
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446246/
https://ncbi.nlm.nih.gov/pubmed/25810326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nmo.12549
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