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Spinal estrogen receptor alpha mediates estradiol-induced pronociception in a visceral pain model in the rat

We previously reported that 17β – estradiol (E2) is pronociceptive in a visceral pain model in the rat. Subcutaneously (s.c.) administered E2 reversed the decrease in the colorectal distention (CRD)-evoked visceromotor response produced by ovariectomy (OVx) and CRD-induced nociceptive responses were...

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Bibliografiske detaljer
Main Authors: Ji, Yaping, Tang, Bin, Traub, Richard J
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079062/
https://ncbi.nlm.nih.gov/pubmed/21392887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2011.01.046
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