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Estrogen alters spinal NMDA receptor activity via a PKA signaling pathway in a visceral pain model in the rat

Pain symptoms in several chronic pain disorders in women, including irritable bowel syndrome, fluctuate with the menstrual cycle suggesting a gonadal hormone component. In female rats, estrogens modulate visceral sensitivity although the underlying mechanism(s) are unknown. In the present study the...

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Detalhes bibliográficos
Main Authors: Tang, Bin, Ji, Yaping, Traub, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2543943/
https://ncbi.nlm.nih.gov/pubmed/18068901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2007.10.017
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