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Inhibition of EGR1 inhibits glioma proliferation by targeting CCND1 promoter

BACKGROUND: Gliomas are the most common primary tumors in central nervous system. The prognosis of the patients with glioma is poor regardless of the development of therapeutic strategies. Its aggressive behavior mainly depends on the potent ability of proliferation. The transcription factor EGR1 (e...

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Bibliographic Details
Published in:J Exp Clin Cancer Res
Main Authors: Chen, Dian-gang, Zhu, Bo, Lv, Sheng-qing, Zhu, Hongfan, Tang, Jinliang, Huang, Changlin, Li, Qingrui, Zhou, Pu, Wang, Dong-lin, Li, Guang-hui
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732438/
https://ncbi.nlm.nih.gov/pubmed/29246166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0656-4
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