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Inhibition of EGR1 inhibits glioma proliferation by targeting CCND1 promoter

BACKGROUND: Gliomas are the most common primary tumors in central nervous system. The prognosis of the patients with glioma is poor regardless of the development of therapeutic strategies. Its aggressive behavior mainly depends on the potent ability of proliferation. The transcription factor EGR1 (e...

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Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Chen, Dian-gang, Zhu, Bo, Lv, Sheng-qing, Zhu, Hongfan, Tang, Jinliang, Huang, Changlin, Li, Qingrui, Zhou, Pu, Wang, Dong-lin, Li, Guang-hui
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732438/
https://ncbi.nlm.nih.gov/pubmed/29246166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0656-4
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