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Crosstalk between DNA methylation and histone acetylation triggers GDNF high transcription in glioblastoma cells
BACKGROUND: Glial cell line-derived neurotrophic factor (GDNF) is highly expressed in glioblastoma (GBM) and blocking its expression can inhibit the initiation and development of GBM. GDNF is a dual promoter gene, and the promoter II with two enhancers and two silencers plays a major role in transcr...
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| Publicado no: | Clin Epigenetics |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7079383/ https://ncbi.nlm.nih.gov/pubmed/32183903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00835-3 |
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