LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

MOTIVATION: LD score regression is a reliable and efficient method of using genome-wide association study (GWAS) summary-level results data to estimate the SNP heritability of complex traits and diseases, partition this heritability into functional categories, and estimate the genetic correlation be...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Zheng, Jie, Erzurumluoglu, A Mesut, Elsworth, Benjamin L, Kemp, John P, Howe, Laurence, Haycock, Philip C, Hemani, Gibran, Tansey, Katherine, Laurin, Charles, Pourcain, Beate St, Warrington, Nicole M, Finucane, Hilary K, Price, Alkes L, Bulik-Sullivan, Brendan K, Anttila, Verneri, Paternoster, Lavinia, Gaunt, Tom R, Evans, David M, Neale, Benjamin M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542030/
https://ncbi.nlm.nih.gov/pubmed/27663502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw613
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados