Načítá se...
Improving the Power of GWAS and Avoiding Confounding from Population Stratification with PC-Select
Using a reduced subset of SNPs in a linear mixed model can improve power for genome-wide association studies, yet this can result in insufficient correction for population stratification. We propose a hybrid approach using principal components that does not inflate statistics in the presence of popu...
Uloženo v:
| Hlavní autoři: | , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Genetics Society of America
2014
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096359/ https://ncbi.nlm.nih.gov/pubmed/24788602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.164285 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|