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Local Joint Testing Improves Power and Identifies Hidden Heritability in Association Studies
There is mounting evidence that complex human phenotypes are highly polygenic, with many loci harboring multiple causal variants, yet most genetic association studies examine each SNP in isolation. While this has led to the discovery of thousands of disease associations, discovered variants account...
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| Publicado no: | Genetics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4937483/ https://ncbi.nlm.nih.gov/pubmed/27182951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.188292 |
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