LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

MOTIVATION: LD score regression is a reliable and efficient method of using genome-wide association study (GWAS) summary-level results data to estimate the SNP heritability of complex traits and diseases, partition this heritability into functional categories, and estimate the genetic correlation be...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Zheng, Jie, Erzurumluoglu, A Mesut, Elsworth, Benjamin L, Kemp, John P, Howe, Laurence, Haycock, Philip C, Hemani, Gibran, Tansey, Katherine, Laurin, Charles, Pourcain, Beate St, Warrington, Nicole M, Finucane, Hilary K, Price, Alkes L, Bulik-Sullivan, Brendan K, Anttila, Verneri, Paternoster, Lavinia, Gaunt, Tom R, Evans, David M, Neale, Benjamin M
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Original Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542030/
https://ncbi.nlm.nih.gov/pubmed/27663502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw613
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