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Role of DNMT3A, TET2, and IDH1/2 Mutations in Pre-Leukemic Stem Cells in Acute Myeloid Leukemia

Aberrant changes in the epigenome are now recognized to be important in driving the development of multiple human cancers including acute myeloid leukemia (AML). Recent advances in sequencing technologies have led to the identification of recurrent mutations in genes that regulate DNA methylation in...

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Detalhes bibliográficos
Publicado no:Int J Hematol
Main Authors: Chan, Steven M., Majeti, Ravindra
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542003/
https://ncbi.nlm.nih.gov/pubmed/23949914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12185-013-1407-8
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