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Pre-leukemic evolution of hematopoietic stem cells – the importance of early mutations in leukemogenesis
Cancer has been shown to result from the sequential acquisition of genetic alterations in a single lineage of cells. In leukemia, increasing evidence has supported the idea that this accumulation of mutations occurs in self-renewing hematopoietic stem cells (HSCs). These HSCs, containing some, but n...
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| 出版年: | Leukemia |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4262622/ https://ncbi.nlm.nih.gov/pubmed/25005245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2014.211 |
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