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Clonal evolution of pre-leukemic hematopoietic stem cells precedes human acute myeloid leukemia
Massively parallel DNA sequencing has uncovered recurrent mutations in many human cancers. In acute myeloid leukemia (AML), cancer genome/exome resequencing has identified numerous recurrently mutated genes with an average of 5 mutations in each case of de novo AML. In order for these multiple mutat...
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Publicado no: | Best Pract Res Clin Haematol |
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Autor principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5419218/ https://ncbi.nlm.nih.gov/pubmed/25455271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beha.2014.10.003 |
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