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Clonal evolution of pre-leukemic hematopoietic stem cells precedes human acute myeloid leukemia

Massively parallel DNA sequencing has uncovered recurrent mutations in many human cancers. In acute myeloid leukemia (AML), cancer genome/exome resequencing has identified numerous recurrently mutated genes with an average of 5 mutations in each case of de novo AML. In order for these multiple mutat...

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Bibliografske podrobnosti
izdano v:Best Pract Res Clin Haematol
Glavni avtor: Majeti, Ravindra
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419218/
https://ncbi.nlm.nih.gov/pubmed/25455271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beha.2014.10.003
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