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Clonal Evolution of Acute Leukemia Genomes

In large part, cancer results from the accumulation of multiple mutations in a single cell lineage that are sequentially acquired and subject to an evolutionary process where selection drives the expansion of more fit subclones. Due to the technical challenge of distinguishing and isolating distinct...

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Detalles Bibliográficos
Publicado en:Oncogene
Main Authors: Jan, Max, Majeti, Ravindra
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538364/
https://ncbi.nlm.nih.gov/pubmed/22349821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.48
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