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Clonal evolution of acute myeloid leukemia highlighted by latest genome sequencing studies

Decades of years might be required for an initiated cell to become a fully-pledged, metastasized tumor. DNA mutations are accumulated during this process including background mutations that emerge scholastically, as well as driver mutations that selectively occur in a handful of cancer genes and con...

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Publicat a:Oncotarget
Autors principals: Zhang, Xuehong, Lv, Dekang, Zhang, Yu, Liu, Quentin, Li, Zhiguang
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295455/
https://ncbi.nlm.nih.gov/pubmed/27474172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10850
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