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Genetic Heterogeneity and Clonal Evolution in Acute Myeloid Leukemia

PURPOSE OF THE REVIEW: Clonal heterogeneity is a significant obstacle to successful treatment of patients with acute myeloid leukemia (AML). Here we review new advances in the understanding of genetic heterogeneity in AML using single cell DNA sequencing technology. RECENT FINDINGS: New genomics and...

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Publicat a:Curr Opin Hematol
Autors principals: Romer-Seibert, Jennifer S., Meyer, Sara E.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731048/
https://ncbi.nlm.nih.gov/pubmed/33186150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000626
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