Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities

Identification of the molecular machinery employed in cancer invasion, but not in normal adult cells, will greatly contribute to cancer therapeutics. Here we found that an ArfGAP, AMAP1/PAG2, is expressed at high levels in highly invasive breast cancer cells, but at very low levels in noninvasive br...

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Bibliographische Detailangaben
Hauptverfasser: Onodera, Yasuhito, Hashimoto, Shigeru, Hashimoto, Ari, Morishige, Masaki, Mazaki, Yuichi, Yamada, Atsuko, Ogawa, Eiji, Adachi, Masashi, Sakurai, Takaki, Manabe, Toshiaki, Wada, Hiromi, Matsuura, Nariaki, Sabe, Hisataka
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC554134/
https://ncbi.nlm.nih.gov/pubmed/15719014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600588
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