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CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery

Expression of AMAP1 correlates well with the invasive phenotypes and malignancy of human primary breast carcinomas. AMAP1 recruits its binding proteins, such as cortactin and paxillin, to sites of Arf6 activation to form invadopodia. A mouse ortholog of AMAP1, ASAP1, is known to bind to CIN85, a bin...

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Bibliografiska uppgifter
Huvudupphovsmän: Nam, Jin-Min, Onodera, Yasuhito, Mazaki, Yuichi, Miyoshi, Hiroyuki, Hashimoto, Shigeru, Sabe, Hisataka
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2007
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794391/
https://ncbi.nlm.nih.gov/pubmed/17255943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601534
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