Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities

Identification of the molecular machinery employed in cancer invasion, but not in normal adult cells, will greatly contribute to cancer therapeutics. Here we found that an ArfGAP, AMAP1/PAG2, is expressed at high levels in highly invasive breast cancer cells, but at very low levels in noninvasive br...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Onodera, Yasuhito, Hashimoto, Shigeru, Hashimoto, Ari, Morishige, Masaki, Mazaki, Yuichi, Yamada, Atsuko, Ogawa, Eiji, Adachi, Masashi, Sakurai, Takaki, Manabe, Toshiaki, Wada, Hiromi, Matsuura, Nariaki, Sabe, Hisataka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554134/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15719014/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600588
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