Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities

Identification of the molecular machinery employed in cancer invasion, but not in normal adult cells, will greatly contribute to cancer therapeutics. Here we found that an ArfGAP, AMAP1/PAG2, is expressed at high levels in highly invasive breast cancer cells, but at very low levels in noninvasive br...

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Udgivet i:EMBO J
Main Authors: Onodera, Yasuhito, Hashimoto, Shigeru, Hashimoto, Ari, Morishige, Masaki, Mazaki, Yuichi, Yamada, Atsuko, Ogawa, Eiji, Adachi, Masashi, Sakurai, Takaki, Manabe, Toshiaki, Wada, Hiromi, Matsuura, Nariaki, Sabe, Hisataka
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2005
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554134/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15719014/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600588
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