IL-22 upregulates epithelial claudin-2 to drive diarrhea and enteric pathogen clearance

Diarrhea is a host response to enteric pathogens, but its impact on pathogenesis remains poorly defined. By infecting mice with the attaching and effacing bacteria Citrobacter rodentium, we defined the mechanisms and contributions of diarrhea and intestinal barrier loss to host defense. Increased pe...

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Detaylı Bibliyografya
Yayımlandı:Cell Host Microbe
Asıl Yazarlar: Tsai, Pei-Yun, Zhang, Bingkun, He, Wei-Qi, Zha, Juan-Min, Odenwald, Matthew A., Singh, Gurminder, Tamura, Atsushi, Shen, Le, Sailer, Anne, Yeruva, Sunil, Kuo, Wei-Ting, Fu, Yang-Xin, Tsukita, Sachiko, Turner, Jerrold R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541253/
https://ncbi.nlm.nih.gov/pubmed/28618266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.05.009
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