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Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain
BACKGROUND: In human carcinomas, overexpression of cortactin correlates with poor prognosis. Cortactin is an F-actin-binding protein involved in cytoskeletal rearrangements and cell migration by promoting actin-related protein (Arp)2/3 mediated actin polymerization. It shares a high amino acid seque...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC554100/ https://ncbi.nlm.nih.gov/pubmed/15710041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-6-15 |
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