Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain

BACKGROUND: In human carcinomas, overexpression of cortactin correlates with poor prognosis. Cortactin is an F-actin-binding protein involved in cytoskeletal rearrangements and cell migration by promoting actin-related protein (Arp)2/3 mediated actin polymerization. It shares a high amino acid seque...

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Main Authors: van Rossum, Agnes GSH, Schuuring-Scholtes, Ellen, Seggelen, Vera van Buuren-van, Kluin, Philip M, Schuuring, Ed
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2005
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC554100/
https://ncbi.nlm.nih.gov/pubmed/15710041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-6-15
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