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The Actin-binding Domain of Cortactin is Dynamic and Unstructured and Affects Lateral and Longitudinal Contacts in F-actin

Cortactin is an F-actin- and Arp2/3 complex-binding protein, implicated in the regulation of cytoskeleton dynamics and cortical actin-assembly. The actin-binding domain of cortactin consists of a 6.5 tandem repeat of a 37-amino acid sequence known as the cortactin repeat (residues 80-325). Using a c...

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Autori principali: Shvetsov, Alexander, Berkane, Emir, Chereau, David, Dominguez, Roberto, Reisler, Emil
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070610/
https://ncbi.nlm.nih.gov/pubmed/19089942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.20328
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