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ADF/cofilin use an intrinsic mode of F-actin instability to disrupt actin filaments

Proteins in the ADF/cofilin (AC) family are essential for rapid rearrangements of cellular actin structures. They have been shown to be active in both the severing and depolymerization of actin filaments in vitro, but the detailed mechanism of action is not known. Under in vitro conditions, subunits...

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Détails bibliographiques
Auteurs principaux: Galkin, Vitold E., Orlova, Albina, VanLoock, Margaret S., Shvetsov, Alexander, Reisler, Emil, Egelman, Edward H.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173606/
https://ncbi.nlm.nih.gov/pubmed/14657234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200308144
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