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ADF/cofilin use an intrinsic mode of F-actin instability to disrupt actin filaments

Proteins in the ADF/cofilin (AC) family are essential for rapid rearrangements of cellular actin structures. They have been shown to be active in both the severing and depolymerization of actin filaments in vitro, but the detailed mechanism of action is not known. Under in vitro conditions, subunits...

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Bibliografiske detaljer
Main Authors: Galkin, Vitold E., Orlova, Albina, VanLoock, Margaret S., Shvetsov, Alexander, Reisler, Emil, Egelman, Edward H.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173606/
https://ncbi.nlm.nih.gov/pubmed/14657234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200308144
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