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ADF/cofilin use an intrinsic mode of F-actin instability to disrupt actin filaments

Proteins in the ADF/cofilin (AC) family are essential for rapid rearrangements of cellular actin structures. They have been shown to be active in both the severing and depolymerization of actin filaments in vitro, but the detailed mechanism of action is not known. Under in vitro conditions, subunits...

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Detalhes bibliográficos
Main Authors: Galkin, Vitold E., Orlova, Albina, VanLoock, Margaret S., Shvetsov, Alexander, Reisler, Emil, Egelman, Edward H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173606/
https://ncbi.nlm.nih.gov/pubmed/14657234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200308144
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