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The utrophin actin-binding domain binds F-actin in two different modes: implications for the spectrin superfamily of proteins

Utrophin, like its homologue dystrophin, forms a link between the actin cytoskeleton and the extracellular matrix. We have used a new method of image analysis to reconstruct actin filaments decorated with the actin-binding domain of utrophin, which contains two calponin homology domains. We find two...

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Detalles Bibliográficos
Main Authors: Galkin, Vitold E., Orlova, Albina, VanLoock, Margaret S., Rybakova, Inna N., Ervasti, James M., Egelman, Edward H.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199260/
https://ncbi.nlm.nih.gov/pubmed/11956227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200111097
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